Here is My Question:
I've been off Tysabri for 11 months and I still feel badly. I've had 2 relapses and 3 infections. I don't know what to do.
I would recommend discussing the possibility of restarting Tysabri with your MS doctor. If your doctor is opposed to restarting Tysabri, ask him/her for specific reasons. If you are not satisfied with his/her answers, ask for another opinion with an MS specialist who is more comfortable with alternative dosing regimens and monitoring protocols for patients on long term Tysabri treatment. Some doctors are uncomfortable with continuing Tysabri in any patient who is JC virus antibody positive regardless of the antibody index or other risk factors. While I respect their point of view, I feel that patients should be offered the option of continuing treatment under a different physician if the patient is competent to make decisions and is aware of the risks involved.
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