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Welcome to the Virtual MS Center!

Ask any question you want about Multiple Sclerosis and one of our experts will answer it as soon as possible.
CLICK HERE TO ASK YOUR QUESTION!

Autologous Hemotopoietic Stem Cell Transplant and Multiple Sclerosis

11/8/2021

0 Comments

 
Here is My Question:
Hi, so, there have been reports of Selma Blair having had a stem cell transplant and she is in remission. Is this something that could assist other Multiple Sclerosis patients? And where would one start to seek out information on this option.

Answer:

Selma Blair underwent a procedure called an autologous hematopoietic stem cell transplant at Northwestern university using a protocol similar to the protocol we use at UCSD. It is a procedure with more short- and long-term risks and side effects than currently approved high efficacy disease modifying therapies. To be a candidate one must meet the following criteria
  1. Be under the age of 45 and preferably under the age of 40
  2. Only relapsing remitting people with MS (no progressive disease) with recent activity (verified relapses or MRI activity) in the prior 2-years despite at least 2 disease modifying therapies 
  3. Must be ambulatory for at least 50 meters (about half the length of a football field)
The procedure involves 4 steps:
  1. We collect your hematopoietic stem cells using a procedure called leukapheresis. we stimulate the release of these cells into your blood stream by giving you cyclophosphamide, a chemotherapy
  2. We give you a large dose of chemotherapy to destroy your remaining lymphocytes.
  3. We give you back your stem cells. These cells migrate to the bone marrow and other immune organs to reform your adaptive immune system
  4. We give you an additional monoclonal antibody called anti-thymocyte globulin to destroy any mature lymphocytes mixed in with the stem cells just infused
The Procedure requires admission to the bone marrow transplantation unit for 10-14 days. People remain severely immunosuppressed for up to 100 days after the procedure.

Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego
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Can I treat bacterial vaginitis with metrinidazole if I have multiple sclerosis?

11/8/2021

0 Comments

 
Here is My Question:
Can I treat Bacterial Vaginitis with Metrinidazole 400mg tablets when I have MS? 

Answer:
There is no MS related contraindication to the use of metronidazole for bacterial vaginitis. This is a prescription antibiotic. Hope you feel better.

Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego
0 Comments

Will my vertigo and bathroom issues go away while taking Ocrevus?

11/8/2021

0 Comments

 
Here is My Question:
I have black holes on my MRI with stem lesions. Will my vertigo and bathroom issues go away with Ocrevus?

Answer:
Whether your "vertigo and bathroom issues" have the potential to remit (i.e. go away) has more to do with the exact cause and duration of the symptoms. Both vertigo and impaired urination require evaluations for causation in most MS patients, particularly those over 40, since other conditions can cause similar symptoms. If determined to be related to MS, it is rare for these symptoms to go away spontaneously once the symptoms have been present continuously for over a year.

Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego
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  • Home
  • About Us
  • Virtual MS Center
    • Q & A for Virtual MS Center
    • Read About Our Virtual MS Center Staff
  • News & Resources
  • Seminar Registration
  • Health & Wellness
  • Blogs
    • Physician Blog >
      • Healthcare Provider Blog
    • Physical Therapy Blog
    • Patient Blog
    • Caregiver Blog
    • Research Blogs >
      • "Ask Dr. Debbie" Research Blog
      • Multiple Perspectives In Multiple Sclerosis Research Blog
  • About MS
    • What is MS?
    • Diagnosis
    • Treatment
    • MS Tips
  • Symptoms
    • Balance and Walking Issues
    • Breathing/Respiratory
    • Bowel Dysfunction
    • Cognitive Dysfunction
    • Crying/Laughing Uncontrollably (PBA)
    • Depression and Anxiety
    • Dizziness/Vertigo
    • Dysphagia
    • Fatigue
    • Foot Drop
    • Hearing or Smell or Taste Changes
    • Heat Sensitivity
    • Leg Weakness
    • Loss of Hand Dexterity and Coordination
    • Memory and Mutliple Sclerosis
    • Migraines
    • Numbness/Tingling/Altered Sensation
    • Nystagmus and Oscillopsia
    • Pain
    • Sexual Dysfunction
    • Sleep Issues
    • Spasticity/Spasms/Cramps
    • Speech/Swallowing
    • Urination/Bowel Problems
    • Vision
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