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What is causing my Restless Leg Syndrome and Spasms?

8/3/2015

 
Here is My Question:
In January of this year I started having a sore neck like I had slept on it wrong, a kink. The first of February I started having numbness in my left hand and a feeling of electricity from the base of my skull running down my spine and across my trapezia muscles, like someone had touch my spine with a low voltage electric wire. Then on March 18th while at work my left arm from my fingertips all the way up to my left earlobe went numb, pins and needles, lack of coordination. I wasn't able to use it to pick up anything at all. The next day I went in to see my GP, and I was sent to get xrays. I was told that it was probably a pinched nerve. 

The xrays came back with a narrowing of the cervical foramen but not enough to cause this much numbness so, he sent me for a cervical MRI w/wo contrast. The results showed a lesion on my spine. Due to the lesion the GP sent me for a brain MRI w/wo contrast. The brain MRI showed no lesions so, the GP told me that no brain lesions ruled out MS. Then I was sent to a neurosurgeon to see what to do about the narrowing of the foramen and the spine lesions. The neurosurgeon did a thorough neuro exam and then told me that he believed that I did have MS and he wanted to do an LP. He did the LP and bloodwork. One week later he told me that I have MS. That was April 29th. I have my first appointment with a neurologist on August 5th. No that I have told you my MS story my question is, in 1998 I was diagnosed with RLS due to spasms in my legs, I was prescribed Requip. Since I started on Requip they have increased my dose from .25mg Q HS to 4mg BID because I get the spasms all during the day and night. Since the diagnosis of MS I have been wondering if the RLS is really MS symptoms? Could the legs and arm spasms be MS and I am taking a high dose of medicine that I don't really need.????? Thanks for any help.

Answer:
It sounds like you’ve experienced a subacute partial transverse myelopathy (PTM). This means you have a problem that developed over several weeks involving one segment (i.e. transverse) of your spinal cord (i.e. Myelopathy) but not the entire segment (i.e. partial). If the neurosurgeon did a lumbar puncture and thought this was MS, then we call this a partial transverse myelitis. This means the problem in the spinal cord is due to inflammation if all the information is correct. You did not mention if you are getting worse. If you did not spontaneously get better, we usually treat this problem with high dose intravenous corticosteroids, if you have no contraindications. There are several causes of a PTM besides MS so you do need a prompt evaluation by a neurologist. Your age and circumstances and other features you may not even be aware of will help the neurologist determine if this is likely caused by MS or something else. So don’t miss your appointment next week.

I am a little unclear on the restless leg syndrome (RLS) diagnosis. Just so we are clear RLS is defined as an irresistible need to move your legs when you are still, much worse at night, because of an unusual discomfort in the legs often described as creepy crawly sensations, tugging, pulling or even pain. To be RLS the discomfort must also cease or significantly decrease shortly after assuming some movement or activity  (e.g. getting up to walk or moving) to be characterized as RLS. Many people with RLS also experience periodic limb movements during the night that interfere with sleep. These are sudden involuntary twitching or jerking movements that lead to frequent awakenings and cause daytime sleepiness.

Muscle spasms at night are different than RLS, but are often confused with RLS, especially in people with problems involving their spinal cords. Spasticity is an increase in muscle tone that creates stiffness with movements that is worse the faster you try to move, particularly with walking. People with spasticity can experience involuntary muscle spasms in the legs that usually get worse when they lie down supine (flat), especially at night when they go to sleep. These can be painful and can cause either forced straightening of the legs or flexion (pulling up into a fetal position). This is not RLS.

Both nocturnal leg spasms and RLS can occur in MS patients but we treat them differently.

Good luck and let us know what happens. 

Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego

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  • Home
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  • Virtual MS Center
    • Q & A for Virtual MS Center
    • Read About Our Virtual MS Center Staff
  • News & Resources
  • Seminar Registration
  • Health & Wellness
  • Blogs
    • Physician Blog >
      • Healthcare Provider Blog
    • Physical Therapy Blog
    • Patient Blog
    • Caregiver Blog
    • Research Blogs >
      • "Ask Dr. Debbie" Research Blog
      • Multiple Perspectives In Multiple Sclerosis Research Blog
  • About MS
    • What is MS?
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  • Symptoms
    • Balance and Walking Issues
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    • Depression and Anxiety
    • Dizziness/Vertigo
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    • Foot Drop
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