Here is My Question:
I was just diagnosed with MS. I've been taking Tecfidera for 6 months and had another MRI and had new lesions. What drug do you suggest?
All therapies are partially effective, and some have proven to be better than others in head to head clinical trials. Because they are partially effective, interval disease activity on the MRI (particularly after a short time on medication before the drug exerts it’s full effect) may not prove the therapy is ineffective or the wrong choice for a given patient situation. There are so many factors to therapy choice and monitoring that I can’t answer your question without evaluating you myself.
I’d suggest meeting with your neurologist and discussing your questions and concerns. Before embarking on a therapy, there should be an understanding and agreement regarding what an adequate response is to the therapy and benchmarks to determine when a therapy is a failure and what the contingency plan is for you.
A. Scott Nielsen, MD MMSc
Neurologist and MS Specialist at Kaiser Permanente
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