I am 54 years old and have been diagnosed with MS for10 years though in hindsite I realize I how symptoms for 10 years prior.
My question is about changing to a different DMT after two years on Copaxone. I’m of thin build and have just run out of options for injection sites.
I have for the last 6 years had no activity on my MRI but have slowly progressed, so now my neurologist believes more progressive disease.
I was on Beta seron for three years, Tysabri three years ( jc negative) and Copaxone one for 2 years. My neurologist wants me now to take Tecfidera. I’m conflicted as what to do and if this really is the best path forward.
I’d suggest speaking to your neurologist about one of the b-cell biologics (Ocrevus, rituximab) or possibly siponimod (similar to gilenya). These therapies have shown ability to slow down the rate of progression (particularly in individuals with signs of recent inflammatory disease activity.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist at Kaiser Permanente