Here is My Question:
Is Tecfidera 120 mg effective as a maintenance dose?
I was diagnosed with RRMS two years ago and have been on Tecfidera since. It appears that the drug is doing a good job controlling my disease; I have not had any new attacks and my MRI results have been stable. However, I began experiencing hair loss about 3 months into the start of the medication, which has continued for almost two years now. My hair is now visibly thin. Other causes of hair loss were investigated and eliminated. My neurologist suggests halving the Tecfidera dose to 120 mg/twice a day and having an MRI done in 3 months. Is Tecfidera 120 mg effective as a maintenance dose? Will halving the dose help with my hair loss?
120mg dosing is off label. The plan to check the MRI at 3 months is likely to screen for asymptomatic disease activity on the lower off label dosing.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist at Kaiser Permanente
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