Here is My Question:
With COVID-19, I completed my Ocrevus treatment April 2019, I haven't gotten a boost since then. Is it safe to travel? Safe to get on a plane?
The answer to this question depends on your risk factors, where you plan to travel and what you plan to do once you arrive at your location?
The main risk factors for serious COVID 19 infections, including death, include age over 60 (especially males), hypertension, diabetes, obesity, vascular disease and significant disability. If you have any of these risk factors you should still be in quarantine at home. If you do not have significant risk factors, I would consider travel only if absolutely necessary and take precautions.
We do not at present know if ocrelizumab increases the risk of more severe COVID-19 infections. If your naive B cells have returned, which is usually the case 6 to 12 months after an ocrevus infusion cycle, you will theoretically be able to develop a humoral immune response against a novel pathogen like COVID-19.
Revere P (Rip) Kinkel, MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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