I have been on Aubagio for almost two years. Is it OK to have the Shingrix vaccine? Everyone tells me it is an inactive vaccine. Thanks.
Yes, it is true that Shingrix is not a live viral vaccine. Use of Shingrix while on a DMT (ie, aubagio) may be blunted due to the MS therapy. Per CDC, if you are negative for the chicken pox virus antibody (meaning you do not have immunity against the chickenpox virus), you should not get this vaccine. Your neurologist can test for this by sending for a VZV IgG antibody titer (blood test). If you are younger than 40, there is a chance that you are negative for the chicken pox antibody (those over than 40, and before the vaccine era for VZV, are likely to have memory immunity for chicken pox and could get the Shingrix vaccine). Before you pursue this vaccine, please discuss with your MS provider as there may be other considerations for this vaccine in your specific case.
A. Scott Nielsen, MD MMSc
Neurologist and MS Specialist at Kaiser Permanente
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