After 8 years on TYSABRI it has become ineffective. Can I go back on avonex? I stopped takng the avnonex ater 10 yeas when I started to have absence seizures. I came off tysabri in november and am not very comfortable with the alternative DMTs. Please advise. Also is it safe to smoke weed while on a DMT?
I am not sure what you mean when you state, “after 8 years of tysabri it has become ineffective.” If this is because of the develop of progressive disease without relapses, it is unlikely that Avonex will be beneficial.
The optimal treatment choice, if there is one, will depend on additional information related to disease course, age, extent of inflammatory activity (relapses and MRI activity) in the past year, prior DMTs besides Avonex and Tysabri and other conditions you may be experiencing.
There should be no harmful interaction between marijuana and DMTs.
Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
Professor of Clinical Neurosciences
University of California San Diego