Here is My Question:
In what circumstance would Rituximab be used as a first line therapy?
Generally, Rituximab would be considered appropriate as a first line therapy in the same circumstances that Ocrevus would be considered as first line therapy. The difference is that Ocrevus is specifically approved by the FDA for treatment of relapsing and primary progressive MS and easier in most circumstances to get approved by insurance carriers for these indications. The exception is Kaiser Permanente insured patients, where Rituximab is part of their formulary for MS treatment.
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
PLEASE NOTE: The information/opinions on this site should be used as an information resource only. This information does not create any patient-HCP relationship, and should not be used as a substitute for professional diagnosis and treatment. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition.