Here is My Question:
Hello, I am JCV positive and have been assured that a 6/8 week interval between each Tysabri is not dangerous as far as developing PML goes, would you agree?
You ask for assurance that something is not "dangerous". Dangerous is a loaded term, especially in medicine. We prefer to compare risk with benefit, the so-called risk/benefit ratio and allow people to make their own decision. So here are the facts as we know it.
Lastly, it is always important to emphasize that all treatments for MS have potentially severe risks. These risks are generally manageable if patients and physicians follow accepted protocols for mitigating these risks. Not adhering to agreed upon dosing schedules, missing visits, forgetting to monitor blood work or failure to monitor MRI scans are all recipes for unsatisfactory and rarely, "dangerous" outcomes.
Revere P (Rip) Kinkel, MDProfessor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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