How is it determined when your RRMS changes its status to the progressive MS diagnosis ? I see my daughter's baseline decline, yet she still has the RRMS status.
When a person develops progressive MS after an initial relapsing remitting course, we call this secondary progressive MS (SPMS). Determining the onset of SPMS is very difficult; in most cases we observe a patient at multiple visits over a period of time, usually 1-5 years, and eventually decide that they are now secondary progressive.
There are certain features that suggest secondary progressive MS but all that is really required is progressive worsening of impairment without significant improvement or an alternative explanation over an interval usually in excess of 6 months. Typical but not required features of secondary progressive MS are the following:
Rip Kinkel, MD
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