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Welcome to the Virtual MS Center!Ask any question you want about Multiple Sclerosis and one of our experts will answer it as soon as possible
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Here is My Question:
I'm going to be starting Rituximab Infusion soon. I have Relapsing MS. Can you explain how this infusion works? Answer: Rituximab is a chimeric monoclonal antibody engineered to bind to and kill any cell in your circulation that has a protein on it’s surface called CD20. CD20 is primarily expressed on the surface of B cells, a subtype of lymphocyte, making this a very selective therapy that leaves the rest of your immune system unaffected. The B cells destroyed by rituximab are thought to be heavily involved in both the development and persistence of the inflammation associated with Multiple Sclerosis. This is the likely reason that Rituximab is so effective in relapsing forms of MS, a stage of the disease where injury to the nervous system is primarily caused by new and persistent inflammation. Revere (Rip) Kinkel MD Professor of Clinical Neurosciences Director of the Multiple Sclerosis Program Clinical Neurosciences Director University of California San Diego
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