Here is My Question:
I have a lumbar puncture (spinal tap) procedure scheduled one day prior to me receiving the second half of my first Ocrevus infusion. Does it matter if I have a spinal tap the day before receiving my Ocrevus infusion? I am a college professor who has tried to schedule all doc appointments & procedures during my students spring break week to avoid having to cancel more classes for my appointments. I had a severe relapse recently and had to alter my class formats and take time off. I would like to avoid taking more if possible. Thank you.
It should make no difference when you undergo the Lumbar puncture if it is being done to diagnose MS. Ocrevus does not cross the blood brain barrier well and does not typically affect intrathecal (within the CSF space) production of immunoglobulin, at least not in the short term. The CSF lymphocyte count may be lower but nothing else that we analyze routinely in clinical practice for MS diagnosis should be affected.
Revere P (Rip) Kinkel, MDProfessor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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