Do I have to wait until my spinal cord shows lesions before I can get diagnosis and treatment for MS?
Here is My Question:
My mother had PPMS and passed away 4 years ago. I contracted Covid in April 2022 and recovered from it. But in Dec 2022, I started experiencing tingling feet, pins and needles in my hands and feet, muscle spasms in my body, hand tremors, heavy feeling in my left arm and legs, cognitive issues and low mood. My brain MRI shows several lesions. My Spinal cord MRI has no lesions and lumbar puncture shows no OCB since I am probably early in the disease course. Do I have to wait until my spinal cord shows lesions ( which means I will have irreparable walking/ balance issues) or positive OCB ( 10% MS patients have no OCB) before I can get diagnosis and treatment for MS?
Excellent question. Establishing a diagnosis of MS is not always easy. You are correct that some individuals do not have oligoclonal bands in the CSF and this may be associated with a type II or III pathological subtype by Claudia Lucchinetti's criteria. I would suggest another opinion with an MS specialist. The amount of information provided in your email is not sufficient to provide more information
Revere P (Rip) Kinkel, MDProfessor of Neurosciences
Director of the Multiple Sclerosis Program
University of California San Diego
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