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Here is My Question:
Could having a low WBC count from being on Gilenya lead to a false test for lyme disease?
It is unlikely that a low white blood count (WBC) from Gilenya would cause either a false positive or false negative Lyme test or any other antibody test.
False positive results can occur if a patient is treated with intravenous immunoglobulin within the past 4 months (half life for intravenous immunoglobulin is 3 to 4 weeks)
False negative results can occur in a patient who is immunoglobulin deficient; technically, this is not a "false negative" result because the patient is truly not making the specified antibodies
This is true for almost any test in which specific antibodies are being measured.
Hope this helps
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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