Here is My Question:
Hello! Back when I was diagnosed with MS I sent Dr. Nielsen a list of supplements (EPA, DHA, d3, b-12 and a b complex) I started taking in an attempt to boost nerve health. He told me that long-term exposure of b6 as pyridoxine can cause peripheral nerve damage that is irreversible and quite painful. My wife, just recently, purchased a plexus dietary supplement that contains b6 as pyridoxine hydrochloride (2.5 mg and suggests 1 to 4 tablets daily).
Is this the same vitamin? Is the chance of causing nerve damage the same for someone who does not have MS?
Thank you to Dr. Nielsen and the rest of the specialists that maintain this site. It's a wonderful resource.
Yes, this is the same and can cause problems with a part of the nervous system called the dorsal root ganglion (which resides next to the spinal cord and relays sensory information). Toxicity with pyridoxine (b6) tends to accumulate over a year or so.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist at Kaiser Permanente
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