Multiple Sclerosis with a totally normal MRI is unusual in this day and age with the technology available. There are several ways that a person can have MS with a “normal” MRI:
1. The MRI is technically inadequate
2. The MRI isn’t really normal; the doctor reading the MRI is wrong. Often what the doctor really means when they say it is normal is that the findings are not diagnostic of MS
3. The MS is confined to the spinal cord, optic nerves, or other regions difficult to image
4. The MS is atypical or another condition all together
Other tests may be useful if the MRI is not diagnostic of MS. Depending on the circumstances it is sometimes best to observe how a person does for a while before plowing into further testing, but this may not be possible if the person perceives their condition is worsening. Before plowing into more testing, it is also useful to get a second opinion. Hope this helps
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