How do you treat radiology isolated syndrome? Especially the muscle tightness. Also, is this the same as CIS?
Radiographically isolated syndrome, by definition, means that there are no symptoms that can be attributed to MRI findings. The MRI was obtained for reasons other than neurologic symptoms from MS but finds lesions consistent with demyelination. Treating this condition is a very personal decision based on MRI patterns and possibly CSF findings. Symptoms that need management are usually ascribed to other conditions and managed according to those guidelines. CIS is a condition where there has been a documented clinic event.
Benjamin M. Greenberg, MD, MHS
Vice Chair of Translational Research and Ambulatory Care
Department of Neurology and Neurotherapeutics
Director, Transverse Myelitis, Neuromyelitis Optica Programs
Co-Director, Pediatric CONQUER Program
UT Southwestern Medical Center