Regarding the time from stopping Rebif to starting Tecfidera. Can you start the change straight away?
When changing from any interferon (including Rebif) to Tecfidera, first make sure that your absolute lymphocyte count is above normal levels and there are no abnormalities in your liver transaminase levels (also referred to as Liver Enzyme tests). These are standard lab tests that your doctor should have checked before starting Tecfidera. If these and other routine lab tests are normal there is no reason to wait between stopping the interferon (Rebif) and starting the Tecfidera
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego