I have 3 lesions on my spinal cord. What could cause this? Does this mean I have JC virus or PML?
I have always hated the term, “lesions”, because it so non-specific. The literal translation is something structurally abnormal. In the context of Multiple sclerosis, a lesion usually refers to a white spot (T2 hyper intense) on MRI. These T2 hyper intensities or white spots are common in both the spinal cord and brain. In fact it is extremely rare for a person to have MS without these white spots on MRI. The good news is that PML does not typically involve the spinal cord so you do not have to be concerned about that diagnosis. If you have MS, then that is the most likely cause of the white spots on your MRI can.
Revere (Rip) Kinkel MD
Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego