Are there any studies on the effect of Methylcobalamin on MS symptoms?
I do not know of any studies related to the specific use of methylcobalamin supplements to treat MS symptoms. Cobalamin supplements, usually cyanocobalamin or hydroxycobalamin, are often taken by MS patients with anecdotal reports of improved energy levels. There are some studies of methycobalamin for diabetic neuropathy and neuropathic pain but the results are mixed. Vitamin B12 supplements are most commonly cyanocobalamin because this form is easier and cheaper to make. Hydoxycobalamin is probably a better supplement but more expensive. Hydroxycobalamin is actually the treatment for cyanide poisoning because it binds and elements cyanide rapidly and effectively. It used to be the preferred supplement in smokers as well.
Rip Kinkel, MD