Ocrevus to rituxan...does it work in same way?
Both Rituximab (Rituxan) and Ocrelizumab (Orevus) bind to the CD20 receptor on B Cells and kill these cells; We know of no problems with people who have switched between these treatment. In fact there are already people who have switched from Rituximab to Ocrevus and some who have switched from Ocrevus to Rituximab without any problems. The switch is usually because of an insurance issue; the health insurer will cover one but not the other.
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego