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If my multiple sclerosis is stable do I need a disease modifying therapy?

11/25/2015

 
Here is My Question:
If your MS is described as inactive or stable does this mean no DMT medicine for you? Wouldn't these medicines prevent further symptoms? I know my neurologist cannot describe DMT's if he describes my MS as stable. What is your advice? I was diagnosed in 2012 in January and no relapses since, just mild symptoms flaring up.
Thank you in advance.
​
Answer:
The terms "active or stable" are usually in reference to the prior year and have nothing to do with an individual’s eligibility for disease modifying therapy (DMT).  Active MS means the individual experienced either a relapse or new or enlarging MRI lesions in the prior year.  
The longer a person with relapsing remitting MS is stable (without relapses or MRI activity) off of a DMT, the less likely a DMT is that important to start. However, we are talking about intervals in excess of 3 years of stability not 1 or 2 years. It is also important to remember that people with progressive MS often get worse over time without experiencing relapses or MRI activity. These individuals tend not to respond well to DMTs if  several years go by with continued worsening despite an absence of “activity".
Hope this helps

Revere (Rip) Kinkel MD
​Director of the Multiple Sclerosis Program
Professor of Clinical Neurosciences
University of California San Diego
Mascha brautigam
11/26/2015 05:44:21 pm

Thank you very much of your advise.My symptoms are chronic.tension headaches since age 17,and last 2 years right leg pain as in neuropathy pain all day.Take Laroxyl which helps but does not disappear.Now having a second time of worsening of symptoms with my leg,resulting in taking Prednison for 5 days.Last time in August the same.My last MRI in January so due for my new one.i believe still have inactive MS but due to moving house/country my symptoms got worse.Prednison is working well.In August Itgink from the heat.Your advise on these symptoms?thanks


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  • Blogs
    • Physician Blog >
      • Healthcare Provider Blog
    • Physical Therapy Blog
    • Patient Blog
    • Caregiver Blog
    • Research Blogs >
      • "Ask Dr. Debbie" Research Blog
      • Multiple Perspectives In Multiple Sclerosis Research Blog
  • About MS
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    • MS Tips
  • Symptoms
    • Balance and Walking Issues
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    • Crying/Laughing Uncontrollably (PBA)
    • Depression and Anxiety
    • Dizziness/Vertigo
    • Dysphagia
    • Fatigue
    • Foot Drop
    • Hearing or Smell or Taste Changes
    • Heat Sensitivity
    • Leg Weakness
    • Loss of Hand Dexterity and Coordination
    • Memory and Mutliple Sclerosis
    • Migraines
    • Numbness/Tingling/Altered Sensation
    • Nystagmus and Oscillopsia
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