Here is My Question:
How do you test to see if the Ocrevus is working?
There is no test that tells us directly if any disease modifying therapy is working. For some therapies it is very easy to determine if the drug is doing what it is supposed to do, but this doesn’t mean that it is helping any particular person control their MS.
For instance, Ocrevus is a monoclonal antibody that binds to and destroys any B cell in your bloodstream expressing a protein on the cell surface called CD20. We can take a blood sample from a person after they are given Ocrevus and it will tell us if the ocrevus did what it is supposed to do; that is, destroy these identified cells. However, this doesn’t mean that the drug is benefiting a particular person with MS. We need to evaluate (by examinations, clinical outcome measures, self- report and MRI) how you are doing over a reasonable period of time after starting Ocrevus, usually 2 to 3 years, to determine if it is able to control your MS.
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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