Here is My Question:
Can Spasticity Be Caused By Brain Lesions in MS?
I’ve am diagnosed with MS and although I do not have any visible lesions on the spine with MRI, I experience generalized stiffness and tightness throughout my body. It is extremely apparent in both legs. I am unable to stretch my legs well when they are out straight and I have to bend my knee to do any type of stretching. This has gotten progressively worse over the past few years.
Is it possible to have spasticity without spinal cord lesions? Are there certain areas of the brain that would be responsible for this?
It is certainly possible for people with MS to have spasticity in the extremities without any discrete lesions visible in the spinal cord. Spasticity can occur as a result of injury anywhere between the cortex of the brain up to but not including the anterior horn cells of the involved region in the spinal cord
Revere (Rip) Kinkel MD
Professor of Clinical Neurosciences
Director of the Multiple Sclerosis Program
Clinical Neurosciences Director
University of California San Diego
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