I have been on Tysabri for 18 months and my numbers for the test for PML is 3.6 I am going on a different medication. Can my numbers lower after time passes?
Yes, antibody index levels can change while on and off Tysabri. The index is not the sole factor to consider for PML risk, of course. The main thing to keep in mind is the choice of therapy that you transition to and when it is started is important in order to lower the risk of rebound MS disease activity coming off Tysabri. Your neurologist can help with that.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist Kaiser Permanente