Are hyperintense signals in the subcortical region of brain a sign of MS??
Hyperintense signals on certain MRI sequences can be seen in MS and a variety of other conditions. To determine if the changes are due to MS depends on the size, shape, location and total pattern seen on a MRI. There are many things that can cause sub cortical changes on a brain MRI other than MS, so the context matters a lot.
Benjamin M. Greenberg, MD, MHS, FAAN, FANA, CRND
Vice Chair, Translational Research and Strategic Initiatives
Director, Transverse Myelitis and Neuromyelitis Optica Program
Co-Director, Pediatric CONQUER Program
Department of Neurology and Neurotherapeutics
Department of Pediatrics