A question from the mom of a pediatric patient who receives his DMT as injections:
Why can't these injection meds be given via an Intrathecal type pump? The whole device is made to dose our meds at whatever needed rate. It only has to be 'refilled' once a month in most cases. What is it about these meds the kids are taking that can't be dosed out this way?
For interferons, the original trials were indeed intrathecal, but glatiramer acetate has not been tried that way. Regardless of their potential to work via an intrathecal route, the need for an invasive procedure and the risks associated with these pumps are the reason injections are preferred. While not as pleasant, they are far safer.
Benjamin M. Greenberg, MD, MHS
Director, Transverse Myelitis, Neuromyelitis Optica and Pediatric Demyelinating Disease Programs
Director, Neurosciences Clinical Research Center
UT Southwestern Medical Center
Childrens Medical Center