I had my spinal tap come back >5 O bands but my MRI shows no lesions. What does this mean?
Oligoclonal bands indicate compartmentalized inflammation in the nervous system. It is not specific to any one disease, and sometimes it can be transient and resolve. 90%+ of MS patients have oligoclonal bands their entire life. Since you have a normal brain scan, it is impossible for me to interpret the lab finding. It would be best to follow up with the doctor who ordered the test to aid in interpretation.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist at Kaiser Permanente