After HSCT is it possibly to get pregnant if I am 26 years old?
Stem cell transplantation (HSCT) is currently in the research phase for individuals with multiple sclerosis (to determine safety, efficacy, and long-term risks). At present, HSCT requires various levels of chemotherapy to aid in the "re-setting" of the immune system. Chemotherapy medications do have the potential to result in "sterilization" of the patient (chemotherapy in general terms affects all dividing cells in the body, including cells in the ovaries and testes). We should learn more about HSCT through current research, but at present, I cannot answer your question with complete confidence. Even with data to come in the future, exposure to conditioning regimens with various forms of chemotherapy could increase the risk of conception difficulty. Approaches to this potential problem include harvesting ova from women and sperm donations from men prior to undergoing treatment
A. Scott Nielsen
Neurologist and MS Specialist at Kaiser Permanente