Can you get RRMS at age 48? If so does that mean it will be a short lived duration of RRMS and go quickly to secondary progressive?
The majority of patients with MS will have onset/diagnosis between the ages of 20 to 50. The age 48 certainly fits this general observation. Based on what you have mentioned, there is nothing to suggest a deviation from expected time of diagnosis to transition to a secondary progressive phase (if that ever occurs). Other factors are important to suggest a more disabling course of MS: 1) time from first to second clinical attack (ie, frequent attacks earlier on are worse than years between attacks; the nature of the MS attacks where motor involvement poses greater risk for disability, etc). This is what we learned from the natural history studies of multiple sclerosis. It is my experience that early treatment with a proven disease modifying therapy is the best chance to mitigate (and hopefully avoid) permanent disability in the future.
I hope this helps.
A. Scott Nielsen MD MMSc
Neurologist and MS Specialist at Kaiser Permanente